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• Martinez Hernandez A, Silbern I, Geffers I, Tatenhorst L, Becker S, Urlaub H, Zweckstetter M, Griesinger C, Eichele G.
  Low-Expressing Synucleinopathy Mouse Models Based on Oligomer-Forming Mutations and C-Terminal Truncation of α-Synuclein.
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• Steffens H, Mott AC, Li S, Wegner W, Švehla P, Kan VWY, Wolf F, Liebscher S, Willig KI.
  Stable but not rigid: Chronic in vivo STED nanoscopy reveals extensive remodeling of spines, indicating multiple drivers of plasticity.
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• Vahsen BF, Lingor P.
  ULK1 as a novel therapeutic target in neurodegeneration.
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• Serin N, Dihazi GH, Tayyeb A, Lenz C, Müller GA, Zeisberg M, Dihazi H.
  Calreticulin Deficiency Disturbs Ribosome Biogenesis and Results in Retardation in Embryonic Kidney Development.
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• Lange F, Agüi-Gonzalez P, Riedel D, Phan NTN, Jakobs S, Rizzoli SO.
  Correlative fluorescence microscopy, transmission electron microscopy and secondary ion mass spectrometry (CLEM-SIMS) for cellular imaging
  PLoS One. 2021 May 10;16(5):e0240768.doi: 10.1371/journal.pone.0240768. eCollection 2021. (PubMed)
• Agüi-Gonzalez P, Guobin B, Gomes de Castro MA, Rizzoli SO, Phan NTN.
  Secondary Ion Mass Spectrometry Imaging Reveals Changes in the Lipid Structure of the Plasma Membranes of Hippocampal Neurons following Drugs Affecting Neuronal Activity.
  ACS Chem Neurosci. 2021 May 5;12(9):1542-1551. doi: 10.1021/acschemneuro.1c00031. Epub 2021 Apr 26. (PubMed)
• Koss DJ, Campesan S, Giorgini F, Outeiro TF.
  Dysfunction of RAB39B-Mediated Vesicular Trafficking in Lewy Body Diseases.
  Mov Disord. 2021 May 3. doi:10.1002/mds.28605. Epub ahead of print. (PubMed)
• Saal KA, Warth Pérez Arias C, Roser AE, Christoph Koch J, Bähr M, Rizzoli SO, Lingor P.
  Rho-kinase inhibition by fasudil modulates pre-synaptic vesicle dynamics.
  J Neurochem. 2021 May;157(4):1052-1068. doi: 10.1111/jnc.15274. Epub 2021 Jan 6. (PubMed)
• Outeiro TF.
  Alpha-synuclein oligomerization and aggregation: A model will always be a model: This is a response to "Monitoring alpha-synuclein oligomerization and aggregation using bimolecular fluorescence complementation assays: What you see is not always what you get". Read the reply on "Alpha-Synuclein oligomerization and aggregation: All models are useful but only if we know what they model". The articles are accompanied by a Preface "How good are cellular models?".
  J Neurochem. 2021 May;157(4):889-890.doi: 10.1111/jnc.15264. Epub 2021 Feb 13. (PubMed)
• Outeiro TF.
  Alpha-Synuclein Antibody Characterization: Why Semantics Matters.
  Neurobiol. 2021 May;58(5):2202-2203. doi: 10.1007/s12035-020-02269-7. Epub 2021 Jan 7. (PubMed)
• Albert K, Raymundo DP, Panhelainen A, Eesmaa A, Shvachiy L, Araújo GR, Chmielarz P, Yan X, Singh A, Cordeiro Y, Palhano FL, Foguel D, Luk KC, Domanskyi A, Voutilainen MH, Huttunen HJ, Outeiro TF, Saarma M, Almeida MS, Airavaara M.
  Cerebral Dopamine Neurotrophic Factor Reduces α-Synuclein Aggregation and Propagation and Alleviates Behavioural Alterations in vivo.
  Mol Ther. 2021 Apr 30:S1525-0016(21)00249-5. doi: 10.1016/j.ymthe.2021.04.035. Epub ahead of print. (PubMed)
• Outeiro TF, Heutink P, Bezard E, Cenci AM.
  From iPS Cells to Rodents and Nonhuman Primates: Filling Gaps in Modeling Parkinson's Disease.
  Mov Disord. 2021 Apr;36(4):832-841. doi: 10.1002/mds.28387. Epub 2020 Nov 16. (PubMed)
• Popova B, Wang D, Rajavel A, Dhamotharan K, Lázaro DF, Gerke J, Uhrig JF, Hoppert M, Outeiro TF, Braus GH.
  Identification of Two Novel Peptides That Inhibit α-Synuclein Toxicity and Aggregation.
  Front Mol Neurosci. 2021 Apr 12;14:659926. doi: 10.3389/fnmol.2021.659926. (PubMed)
• Erskine D, Koss D, Korolchuk VI, Outeiro TF.
  Lipids, lysosomes and mitochondria: insights into Lewy body formation from rare monogenic disorders.
  Acta Neuropathol. 2021 Apr;141(4):511-526. doi: 10.1007/s00401-021-02266-7. Epub 2021 Jan 30. (PubMed)
• Dominguez-Meijide A, Parrales V, Vasili E, González-Lizárraga F, König A, Lázaro DF, Lannuzel A, Haik S, Del Bel E, Chehín R, Raisman-Vozari R, Michel PP, Bizat N, Outeiro TF.
  Doxycycline inhibits α-synuclein-associated pathologies in vitro and in vivo.
  Neurobiol Dis. 2021 Apr;151:105256. doi: 10.1016/j.nbd.2021.105256. Epub 2021 Jan 8. (PubMed)
• Outeiro TF.
  Emerging concepts in synucleinopathies.
  Acta Neuropathol. 2021 Apr;141(4):469-470. doi: 10.1007/s00401-021-02290-7. Epub 2021 Feb 24. (PubMed)
• Roggenkamp HG, Khansahib I, Hernandez LC, Zhang Y, Lodygin D, Krüger A, Gu F, Möckl F, Löhndorf A, Wolters V, Woike D, Rosche A, Bauche A, Schetelig D, Werner R, Schlüter H, Failla AV, Meier C, Fliegert R, Walseth TF, Flügel A, Diercks BP, Guse AH.
  HN1L/JPT2: A signaling protein that connects NAADP generation to Ca 2+ microdomain formation.
  Sci Signal. 2021 Mar 23;14(675):eabd5647. doi: 10.1126/scisignal.abd5647. PMID: 33758062. (PubMed)
• Medina L, González-Lizárraga F, Dominguez-Meijide A, Ploper D, Parrales V, Sequeira S, Cima-Omori MS, Zweckstetter M, Del Bel E, Michel PP, Outeiro TF, Raisman-Vozari R, Chehín R, Socias SB.
  Doxycycline Interferes With Tau Aggregation and Reduces Its Neuronal Toxicity.
  Front Aging Neurosci. 2021 Mar 22;13:635760. doi: 10.3389/fnagi.2021.635760. (PubMed)
• Jacinto S, Guerreiro P, de Oliveira RM, Cunha-Oliveira T, Santos MJ, Grazina M, Rego AC, Outeiro TF.
  MPV17 Mutations Are Associated With a Quiescent Energetic Metabolic Profile.
  Front Cell Neurosci. 2021 Mar 17;15:641264. doi:10.3389/fncel.2021.641264. (PubMed)
• Jähne S, Mikulasch F, Heuer HGH, Truckenbrodt S, Agüi-Gonzalez P, Grewe K, Vogts A, Rizzoli SO, Priesemann V.
  Presynaptic activity and protein turnover are correlated at the single-synapse level.
  Cell Rep. 2021 Mar 16;34(11):108841.doi: 10.1016/j.celrep.2021.108841. (PubMed)
• Dihazi H, Schwarze K , Patschan S, Müller GA, Ritter O, Zeisberg M, Patschan D.
  PAC-Mediated AKI Protection Is Critically Mediated but Does Not Exclusively Depend on Cell-Derived Microvesicles.
  Int. J. Nephrol. 2021 Mar 9;2021:8864183.doi: 10.1155/2021/8864183. eCollection 2021. (PubMed)
• Reshetniak S, Rizzoli SO.
  The vesicle cluster as a major organizer of synaptic composition in the short-term and long-term.
  Curr Opin Cell Biol. 2021 Mar 8;71:63-68. doi: 10.1016/j.ceb.2021.02.007. Online ahead of print. (PubMed)
• Hintze A, Gültas M, Semmelhack EA, Wichmann C.
  Ultrastructural maturation of the endbulb of Held active zones comparing wild-type and otoferlin-deficient mice.
  i.Science. 2021 Mar 8;24(4):102282.doi: 10.1016/j.isci.2021.102282. eCollection 2021 Apr 23. (PubMed)
• Popova B, Wang D, Pätz C, Akkermann D, Lázaro DF, Galka D, Kolog Gulko M, Bohnsack MT, Möbius W, Bohnsack KE, Outeiro TF, Braus GH.
  DEAD-box RNA helicase Dbp4/DDX10 is an enhancer of α-synuclein toxicity and oligomerization.
  PLoS Genet. 2021 Mar 3;17(3):e1009407. doi: 10.1371/journal.pgen.1009407. (PubMed)
• Winkler A, Wrzos C, Haberl M, Weil MT, Gao M, Möbius W, Odoardi F, Thal DR, Chang M, Opdenakker G, Bennett JL, Nessler S, Stadelmann C.
  Blood-brain barrier resealing in neuromyelitis optica occurs independently of astrocyte regeneration.
  J Clin Invest 2021 Mar 1;131(5):e141694.doi: 10.1172/JCI141694. (PubMed)
• Jafari M, Schumacher AM, Snaidero N, Ullrich Gavilanes EM, Neziraj T, Kocsis-Jutka V , Engels D, Jürgens T, Wagner I, Weidinger JDF, Schmidt SS, Beltrán E, Hagan N, Woodworth L, Ofengeim D, Gans J, Wolf F, Kreutzfeldt M, Portugues R, Merkler D, Misgeld T, Kerschensteiner M.
  Phagocyte-mediated synapse removal in cortical neuroinflammation is promoted by local calcium accumulation.
  Nat Neurosci. 2021 Mar;24(3):355-367. doi: 10.1038/s41593-020-00780-7. Epub 2021 Jan 25. (PubMed)
• Ribas VT, Vahsen BF, Tatenhorst L, Estrada V, Dambeck V, Alves Almeida R, Bähr M, Michel U, Koch JC, Müller HW, Lingor P.
  AAV-mediated inhibition of ULK1 promotes axonal regeneration in the central nervous system in vitro and in vivo.
  Cell Death Dis. 2021 Feb 26;12(2):213.doi: 10.1038/s41419-021-03503-3. (PubMed)
• Kilisch M, Götzke H, Gere-Becker M, Crauel A, Opazo F, Frey S.
  Discovery and Characterization of an ALFA-Tag-Specific Affinity Resin Optimized for Protein Purification at Low Temperatures in Physiological Buffer.
  Biomolecules. 2021 Feb 12;11(2):269. doi: 10.3390/biom11020269. (PubMed)
• Brás IC, Outeiro TF.
  Alpha-Synuclein: Mechanisms of Release and Pathology Progression in Synucleinopathies.
  Cells. 2021 Feb 12;10(2):375. doi:10.3390/cells10020375. (PubMed)
• Löhndorf A, Hosang L, Dohle W, Odoardi F, Waschkowski S-A, Rosche A, Bauche A, Winzer R, Tolosa E, Windhorst S, Marry S, Flügel A, Potter BVL, Diercks B-P, Guse AH.
  2-Methoxyestradiol and its derivatives inhibit store-operated Ca 2+ entry in T cells: Identification of a new and potent inhibitor.
  Biochim Biophys Acta Mol Cell Res. 2021 Feb 10;1868(6):118988.doi: 10.1016/j.bbamcr.2021.118988. Epub 2021 Feb 10. (PubMed)
• Dankovich TM, Rizzoli SO.
  Challenges facing quantitative large-scale optical super-resolution, and some simple solutions.
  iScience. 2021 Feb 3;24(3):102134. doi: 10.1016/j.isci.2021.102134. (PubMed)
• Outeiro TF, Krisko A.
  Reply to: "Parkinson's Disease and COVID-19: Do We Need to Be More Patient?".
  Mov Disord. 2021 Feb;36(2):278-279.doi: 10.1002/mds.28482. (PubMed)
• Filippou PS, Outeiro TF.
  Cancer and Parkinson's Disease: Common Targets, Emerging Hopes.
  Mov Disord. 2021 Feb;36(2):340-346. doi: 10.1002/mds.28425. Epub 2020 Dec 21. (PubMed)
• Bonnin EA, Fornasiero EF, Lange F, Turck CW, Rizzoli SO.
  NanoSIMS observations of mouse retinal cells reveal strict metabolic controls on nitrogen turnover.
  BMC Mol Cell Biol. 2021 Jan 11;22(1):5. doi: 10.1186/s12860-020-00339-1. Epub 2020 Dec 21. (PubMed)
• Berghoff SA, Spieth L, Sun T,Hosang L, Schlaphoff L, Depp C, Düking T, Winchenbach J, Neuber J, Ewers D, Scholz P, van der Meer F, Cantuti-Castelvetri L, Sasmita AO, Meschkat M, Ruhwedel T, Möbius W, Sankowski R, Prinz M, Huitinga I, Sereda MW, Odoardi F, Ischebeck T, Simons M, Stadelmann-Nessler C, Edgar JM, Nave KA, Saher G.
  Microglia facilitate repair of demyelinated lesions via post-squalene sterol synthesis.
  Nat Neurosci 2021 Jan;24(1):47-60. doi: 10.1038/s41593-020-00757-6. Epub 2020 Dec 21. (PubMed)
• Truckenbrodt S, Rizzoli SO.
  Simple multi-color super-resolution by X10 microscopy.
  Methods Cell Biol.2021;161:33-56. doi: 10.1016/bs.mcb.2020.04.016. Epub 2020 May 27. (PubMed)
• Klionsky DJ, ...Lingor P, ... Outeiro TF, ... Tong CK.
  Guidelines for the use and interpretation of assays for monitoring autophagy.
  Autophagy. 2021 Jan;17(1):1-382. doi: 10.1080/15548627.2020.1797280. Epub 2021 Feb 8. (PubMed)
• Fonseca-Fonseca LA, da Silva VDA, Wong-Guerra M, Ramírez-Sánchez J, Yaquis ASP, Ochoa-Rodríguez E, Verdecia-Reyes Y, de Araújo FM, Santana RC, Outeiro TF, Costa SL, Núñez-Figueredo Y.
  JM-20 protects against 6-hydroxydopamine-induced neurotoxicity in models of Parkinson's disease: Mitochondrial protection and antioxidant properties.
  Neurotoxicology. 2021 Jan;82:89-98. doi: 10.1016/j.neuro.2020.11.005. Epub 2020 Nov 21. (PubMed)

• Sograte-Idrissi S, Schlichthaerle T, Duque-Afonso CJ, Alevra M, Strauss S, Moser T, Jungmann R, Rizzoli SO, Opazo F.
  Correction: Circumvention of common labelling artefacts using secondary nanobodies.
  Nanoscale. 2020 Dec 23;12(48):24543. doi: 10.1039/d0nr90279a. (PubMed)
• Perego E, Reshetniak S, Lorenz C, Hoffmann C, Milovanović D, Rizzoli SO, Köster S.
  A minimalist model to measure interactions between proteins and synaptic vesicles.
  Sci Rep. 2020 Dec 3;10(1):21086. doi: 10.1038/s41598-020-77887-1. (PubMed)
• Dominguez-Meijide A, Vasili E, Outeiro TF.
  Pharmacological Modulators of Tau Aggregation and Spreading.
  Brain Sci. 2020 Nov 13;10(11):858.doi: 10.3390/brainsci10110858. (PubMed)
• Korchak S, Jagtap A, Glöggler S.
  Signal-enhanced real-time magnetic resonance of enzymatic reactions at millitesla fields.
  Chem. Sci. 2020 Oct DOI: 10.1039/d0sc04884d. (pubs.rsc)
• Hentrich T, Wassouf Z, Ehrhardt C, Haas E, Mills JD, Aronica E, Outeiro TF, Hübener-Schmid J, Riess O, Casadei N, Schulze-Hentrich JM.
  Increased expression of myelin-associated genes in frontal cortex of SNCA overexpressing rats and Parkinson's disease patients.
  Aging (Albany NY). 2020 Oct 5;12(19):18889-18906. doi: 10.18632/aging.103935. Online ahead of print. (PubMed)
• Reshetniak S, Fernández-Busnadiego R, Müller M, Rizzoli SO, Tetzlaff C.
  Quantitative Synaptic Biology: A Perspective on Techniques, Numbers and Expectations.
  Int J Mol Sci. 2020 Oct 2;21(19):7298. doi: 10.3390/ijms21197298 (PubMed)
• Domingues R, Lippi A, Setz C, Outeiro TF, Krisko A.
  SARS-CoV-2, immunosenescence and inflammaging: partners in the COVID-19 crime.
  Aging (Albany NY). 2020 Sep 29;12(18):18778-18789.doi: 10.18632/aging.103989. Online ahead of print. (PubMed)
• Pasterkamp RJ, Burk K.
  Axon guidance receptors: Endocytosis, trafficking and downstream signaling from endosomes.
  Prog Neurobiol. 2020 Sep 28:101916. doi: 10.1016/j.pneurobio.2020.101916. Epub ahead of print. (PubMed)
• Lipphardt M, Dihazi H, Maas JH, Schäfer AK, Amlaz SI, Ratliff BB, Koziolek MJ, Wallbach M.
  Syndecan-4 as a Marker of Endothelial Dysfunction in Patients with Resistant Hypertension.
  J. Clin.Med. 2020 Sep 22;9(9):3051.doi: 10.3390/jcm9093051.PMID: 32971813 (PubMed)
• Mamone S, Schmidt AB, Schwaderlapp N, Lange T, von Elverfeldt D, Hennig J, Glöggler S.
  Localized singlet-filtered MRS in vivo.
  NMR Biomed. 2020 Sep 1;e4400. doi: 10.1002/nbm.4400. Online ahead of print. (PubMed)
• Menezes R, Foito A, Jardim C, Costa I, Garcia G, Rosado-Ramos R, Freitag S, Alexander CJ, Outeiro TF, Stewart D, Santos CN.
  Bioprospection of Natural Sources of Polyphenols with Therapeutic Potential for Redox-Related Diseases.
  Antioxidants (Basel). 2020 Aug 26;9(9):789.doi: 10.3390/antiox9090789. (PubMed)
• Morato Torres CA, Wassouf Z, Zafar F, Sastre D, Outeiro TF , Schüle B.
  The Role of Alpha-Synuclein and Other Parkinson's Genes in Neurodevelopmental and Neurodegenerative Disorders.
  Review, Int J Mol Sci. 2020 Aug 10;21(16):5724.doi: 10.3390/ijms21165724. (PubMed)
• Koss DJ, Bondarevaite O, Adams S, Leite M, Giorgini F, Attems J, Outeiro TF.
  RAB39B is redistributed in dementia with Lewy bodies and is sequestered within aβ plaques and Lewy bodies.
  Brain Pathol. 2020 Aug 6.doi: 10.1111/bpa.12890. Online ahead of print. (PubMed)
• Harris SS, Wolf F, De Strooper B, Busche MA.
  Tipping the Scales: Peptide-Dependent Dysregulation of Neural Circuit Dynamics in Alzheimer's Disease.
  Neuron. 2020 Aug 5;107(3):417-435.doi: 10.1016/j.neuron.2020.06.005. Epub 2020 Jun 23. (PubMed)
• Dominguez-Meijide A, Vasili E, König A, Cima-Omori MS, Ibáñez de Opakua A, Leonov A, Ryazanov S, Zweckstetter M, Griesinger C, Outeiro TF.
  Effects of pharmacological modulators of α-synuclein and tau aggregation and internalization.
  Sci Rep. 2020 Jul 30;10(1):12827.doi: 10.1038/s41598-020-69744-y. (PubMed)
• Bonnin EA, Rizzoli SO.
  Novel Secondary Ion Mass Spectrometry Methods for the Examination of Metabolic Effects at the Cellular and Subcellular Levels.
  Front Behav Neurosci.2020 Jul 20;14:124.doi: 10.3389/fnbeh.2020.00124. eCollection 2020. (PubMed)
• Dihazi GH, Eltoweissy M, Jahn O, Tampe B, Zeisberg M, Wülfrath HS, Müller GA, Dihazi H.
  The Secretome Analysis of Activated Human Renal Fibroblasts Revealed Beneficial Effect of the Modulation of the Secreted Peptidyl-Prolyl Cis-Trans Isomerase A in Kidney Fibrosis.
  Cells. 2020 Jul 18;9(7):1724.doi: 10.3390/cells9071724. PMID:32708451;PMC7407823 (PubMed)
• Mann FA, Herrmann N, Opazo F, Kruss S.
  Quantum Defects as a Toolbox for the Covalent Functionalization of Carbon Nanotubes with Peptides and Proteins.
  Angew Chem Int Ed Engl 2020 Sep 28;59(40):17732-17738. doi: 10.1002/anie.202003825. Epub 2020 Jul 13. (PubMed)
• Belo RF, Martins MLF, Shvachiy L, Costa-Coelho T, de Almeida-Borlido C, Fonseca-Gomes J, Neves V, Vicente Miranda H, Outeiro TF, Coelho JE, Xapelli S, Valente CA, Heras M, Bardaji E, Castanho MARB, Diógenes MJ, Sebastião AM.
  The Neuroprotective Action of Amidated-Kyotorphin on Amyloid β Peptide-Induced Alzheimer's Disease Pathophysiology.
  Front Pharmacol. 2020 Jul 9;11:985.doi: 10.3389/fphar.2020.00985. eCollection 2020. (PubMed)
• Sato M, Mizuta K, Islam T, Kawano M, Sekine Y, Takekawa T, Gomez-Dominguez D, Schmidt A, Wolf F, Kim K, Yamakawa H, Ohkura M, Lee MG, Fukai T, Nakai J, Hayashi Y.
  Distinct Mechanisms of Over-Representation of Landmarks and Rewards in the Hippocampus.
  Cell Rep. 2020 Jul 7;32(1):107864.doi: 10.1016/j.celrep.2020.107864. (PubMed)
• Reshetniak S, Ußling JE, Perego E, Rammner B, Schikorski T, Fornasiero EF, Truckenbrodt S, Köster S, Rizzoli SO.
  A comparative analysis of the mobility of 45 proteins in the synaptic bouton.
  EMBO J. 2020 Aug 17;39(16):e104596.doi: 10.15252/embj.2020104596. (PubMed)
• Schilde LM, Steinbach S, Serschnitzki B, Maass F, Bähr M, Lingor P, Marcus K, May C.
  Human cerebrospinal fluid data for use as spectral library, for biomarker research
  Data Brief. 2020 Jul 19;32:106048.doi: 10.1016/j.dib.2020.106048. eCollection 2020 Oct. (PubMed)
• Outeiro TF, Krisko A.
  Reply to: SARS-CoV-2 as a Potential Trigger of Neurodegenerative Diseases
  Mov Disord. 2020 Jul;35(7):1106-1107.doi: 10.1002/mds.28178. (PubMed)
• Joppe K, Nicolas JD, Grünewald TA, Eckermann M, Salditt T, Lingor P.
  Elemental quantification and analysis of structural abnormalities in neurons from Parkinson's-diseased brains by X-ray fluorescence microscopy and diffraction.
  Biomed Opt Express. 2020 Jun 2;11(7):3423-3443. doi: 10.1364/BOE.389408. eCollection 2020 Jul 1. (PubMed)
• JeJean P, Anttonen T, Michanski S, de Diego AMG, Steyer AM, Neef A, Oestreicher D, Kroll J, Nardis N, Pangršič T, Möbius W, Ashmore J, Wichmann C, Moser T.
  Macromolecular and electrical coupling between inner hair cells in the rodent cochlea
  Nat Commun. 2020 Jun 25;11(1):3208. doi: 10.1038/s41467-020-17003-z.  (PubMed)
• Gerdes C, Waal N, Offner T, Fornasiero EF, Wender N, Verbarg H, Manzini I, Trenkwalder C, Mollenhauer B, Strohäker T, Zweckstetter M, Becker S, Rizzoli SO, Basmanav FB, Opazo F.
  A nanobody-based fluorescent reporter reveals human α-synuclein in the cell cytosol
  Nat Commun. 2020 Jun 1;11(1):2729.doi: 10.1038/s41467-020-16575-0. (PubMed)
• Maass F, Rikker S, Dambeck V, Warth C, Tatenhorst L, Csoti I, Schmitz M, Zerr I, Leha A, Bähr M, Lingor P.
  Increased alpha-synuclein tear fluid levels in patients with Parkinson’s disease.
  Sci Rep.2020 May 22;10(1):8507.doi: 10.1038/s41598-020-65503-1. (PubMed)
• Santos PI, Outeiro TF.
  Protein trapping leads to altered synaptic proteostasis in synucleinopathies.
  Review, FEBS J. 2020 May 13.doi: 10.1111/febs.15364. Online ahead of print. (PubMed)
• Cukierman DS, Lázaro DF, Sacco P, Ferreira PR, Diniz R, Fernández CO, Outeiro TF, Rey NA.
  X1INH, an improved next-generation affinity-optimized hydrazonic ligand, attenuates abnormal copper(i)/copper(ii)-α-Syn interactions and affects protein aggregation in a cellular model of synucleinopathy.
  Dalton Trans. 2020 May 11.doi: 10.1039/d0dt01138j. Online ahead of print. (PubMed)
• Brás IC, Dominguez-Meijide A, Gerhardt E, Koss D, Lázaro DF, Santos PI, Vasili E, Xylaki M, Outeiro TF.
  Synucleinopathies: Where we are and where we need to go.
  Review Neurochem. 2020 May;153(4):433-454.doi: 10.1111/jnc.14965. Epub 2020 Feb 19. (PubMed)
• Vicente Miranda H, Chegão A, Oliveira MS, Fernandes Gomes B, Enguita FJ, Outeiro TF.
  Hsp27 reduces glycation-induced toxicity and aggregation of alpha-synuclein.
  FASEB J. 2020 May;34(5):6718-6728.doi: 10.1096/fj.201902936R. Epub 2020 Apr 7. (PubMed)
• Vahsen BF, Ribas VT, Sundermeyer J, Boecker A, Dambeck V, Lenz C, Shomroni O, Caldi Gomes L, Tatenhorst L, Barski E, Roser AE, Michel U, Urlaub H, Salinas G, Bähr M, Koch JC, Lingor P.
  Inhibition of the autophagic protein ULK1 attenuates axonal degeneration in vitro and in Vivo, enhances translation, and modulates splicing.
  Cell Death Differ. 2020 Apr 27. doi: 10.1038/s41418-020-0543-y. Online ahead of print. (PubMed)
• Lippi A, Domingues R, Setz C, Outeiro TF, Krisko A.
  SARS-CoV-2: At the Crossroad Between Aging and Neurodegeneration.
  Mov Disord. 2020 May;35(5):716-720.doi: 10.1002/mds.28084. Epub 2020 Apr 24. (PubMed)
• Lázaro DF, Outeiro TF.
  The Interplay Between Proteostasis Systems and Parkinson's Disease.
  Review, Adv Exp Med Biol. 2020;1233:223-236.doi: 10.1007/978-3-030-38266-7_9. (PubMed)
• Francelle L, Outeiro TF, Rappold GA.
  Inhibition of HDAC6 activity protects dopaminergic neurons from alpha-synuclein toxicity.
  Sci Rep. 2020 Apr 8;10(1):6064.doi: 10.1038/s41598-020-62678-5. (PubMed)
• Vale N , Alves C, Sharma V, Lázaro DF, Silva S, Gomes P, Outeiro TF.
  A new MAP-Rasagiline conjugate reduces α-synuclein inclusion formation in a cell model.
  Pharmacol Rep. 2020 Apr;72(2):456-464.doi: 10.1007/s43440-019-00032-x. Epub 2020 Jan 15. (PubMed)
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